Cough Syrup In Bangladesh

Cough is very common among Bangladeshi people mostly because of the air pollution and frequent change in weather. Therefore, cough syrup is one of the most used medicines in Bangladesh. There are various types of cough syrup available that you can use for the temporary relief of cough, sneezing, or runny nose. Below you will find detailed information about the best cough syrup in Bangladesh. 

List Of Best Cough Syrup In Bangladesh

Honeybas Syrup

  • Herbal cough syrup [Adhatoda Vasica]
  • ACME Laboratories Ltd.

Composition

Each teaspoon full (5 ml) of syrup contains extracts of-

  • Adhatoda vasica 0.68 gm
  • Piper longum 0.14 gm
  • Glycyrrhiza glabra 6.78 mg
  • Trikatu (Piper nigrum, Zingiber officinale) 20.34 mg
  • Terminalia chebula 73.24 mg
  • Vitis venifera 0.14 gm
  • Acorus calamus 6.78 mg
  • Saussurea lappa 6.78 mg
  • Syzygium aromaticum 6.78 mg
  • Trizatak (Cinnamomum zeylanicum, Elettaria cardamomum, Cinnamomum tamala) 20.34 mg
  • Pistacia integerrima 6.78 mg
  • Myrica nagi 6.78 mg
  • Woodfordia fruticosa 1.14 mg.

Indications

This herbal cough syrup liquefies phlegm. It soothes irritation of the throat. Helps to relieve hoarseness. It is a remedy for all types of cough such as dry irritable cough, allergic & smokers cough.

Description

This syrup is a preparation of a combination of effective herbs which is helpful in all types of cough & cold. The used herbs are well tolerated, safe & non-sedating with potent antiallergic properties. DEVAS syrup is good for both children and adults. It is free of side effects.

  • Adhatoda vasica (Basok): Relieves cough & bronchial spasm. It liquefies mucous.
  • Piper longum (Pipul): Relieves cold allergy & asthma.
  • Glycyrrhiza glabra (Jashthi Modhu) : Relieves irritation of throat. Enhances the immune system. It is anti-inflammatory, demulcent & expectorant.
  • Piper nigrum (Marich): It is fungistatic, bacteriostatic & anti-inflammatory.
  • Zingiber officinale (Shunthi): It is antihistaminic. Very much effective in common cold.
  • Terminalia chebula (Haritaki): It removes toxin from the body. It has beneficial effect on all tissues.
  • Vitis venifera (Kismiss): Relieves cough and general tonic.
  • Acorus calamus (Bacha): Helps in bronchial catarrh & intermittent fever.
  • Saussurea lappa (Kur): It is antiseptic & disinfectant. It is very useful in bronchial asthma.
  • Syzygium aromaticum (Labango): Useful in cough & other respiratory diseases. It prevents bad breath.
  • Cinnamomum zeylanicum (Darchini): It is antibacterial & antifungal and relieves cough due to its soothing action.
  • Elettaria cardamomum (Elachi): It is aromatic in nature and shows antimicrobial activity.
  • Cinnamomum tamala (Tejpata): It is a tonic & appetizer agent.
  • Pistacia integerrima (Kakra sringi): It helps in asthma.
  • Myrica nagi ( Kotfal): It is a remedy for sore throat.
  • Woodfordia fruticosa (Daiful): It is good anti-infective agent and is useful in relieving cough due to its soothing action.
  • Tulsi extract & other ingredients: Tulsi extract & some other ingredients are added to DEVAS syrup for relieving acute cough.

Dosage & Administration

  • Children under 12 years: 1-2 teaspoonful (5-10 ml) 2-3 times a day. ‘
  • Adult: 3 teaspoonful (15 ml) 2-3 times a day.
  • Some warm water may be added for better results.

Side Effects

This syrup is proven as safe. It is well tolerated. In high dose diarrhea, vomiting may occur.

Storage Conditions

Keep out of reach of children. Keep away from direct sunlight. Store in a cool and dry place.

Joshina Powder For Suspension

  • Herbal cough syrup [Glycyrrhiza Glabra]
  • 6 gm/sachet
  • Hamdard Bangladesh

Composition

Each sachet contains-

  • Licorice (Glycyrrhiza glabra): 1.34 gm
  • Sebesten Plum (Cordia dichotoma): 1.34 gm
  • Common Mallow (Malva sylvestris): 0.71 gm
  • Marsh Mallow (Althaea officinalis): 0.54 gm
  • Violet (Viola odorata): 0.45 gm
  • Borage (Borago officinalis): 0.36 gm
  • Chinese Jujube (Zizyphus jujuba): 0.27 gm

Indications

This syrup is indicated in-

  • Cough
  • Catarrh
  • Catarrhal fever & Catarrhal pain
  • Headache & Sore throat
  • Bronchitis
  • Tonsillitis
  • Hoarseness of voice

Pharmacology

It contains Licorice (Glycyrrhiza glabra), Sebesten Plum (Cordia dichotoma), Common Mallow (Malva sylvestris), Marsh Mallow (Althaea officinalis) and other valuable natural ingredients, which have been recognized as the most efficacious herbal cure for cough cold, bronchitis and inflammatory diseases of the respiratory tract.

Dosage & Administration

1 sachet of Joshina be dissolved in a cup of hot water to be taken 2-3 times daily or as directed by the physician. If sweetened with 2 or 3 crushed Sualin tablets, it enhances its effects.

Side Effects

No significant side effect has been observed in proper dosage.

Storage Conditions

Store at cool and dry place, protect from light.

Sudocof Syrup

  • Dextromethorphan + Pseudoephedrine + Triprolidine
  • (10 mg+30 mg+1.25 mg)/5 ml
  • Incepta Pharmaceuticals Ltd.

Composition

Each 5 ml syrup contains-

  • Dextromethorphan Hydrobromide 10 mg
  • Pseudoephedrine Hydrochloride 30 mg
  • Triprolidine Hydrochloride 1.25 mg

Indications

This is indicated for the symptomatic relief of upper respiratory tract disorders accompanied by non-productive cough which benefits from the administration of a nasal decongestant, a histamine H1 receptor antagonist and an antitussive combination.

Pharmacology

Dextromethorphan, a centrally-acting antitussive agent, depresses the medullary cough center through sigma receptor stimulation, resulting to decreased sensitivity of cough receptors and interruption of cough impulse transmission.

Pseudoephedrine is both an α-and β-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of α-adrenergic receptors of the respiratory mucosa. It also directly stimulates β-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.

Triprolidine binds to the histamine H1 receptor. This block the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Dosage & Administration

Adults: 2 tea-spoon three times daily

Children: Over 12 years: 2 tea-spoon three times daily.

6 to 12 years: 1 tea-spoon three times daily

2 to 5 years: 1/2 tea-spoon three times daily

6 months to 2 years: 1/4 tea-spoon three times daily or on advice of a physician only.

Side Effects

Central nervous system depression or excitation may occur, drowsiness being reported most frequently. Sleep disturbance and rarely, hallucinations have been reported. Skin rashes with without irritation, tachycardia, and dryness of mouth, nose, and throat have occasionally been reported. Urinary retention has been reported occasionally in male patients in which prostatic enlargement could be an important predisposing.

Storage Conditions

Store in a dry & cool place, do not refrigerate. Protect from direct sunlight

Brofex Syrup

  • Dextromethorphan Hydrobromide
  • 10 mg/5 ml
  • Square Pharmaceuticals Ltd.

Indications

Dextromethorphan is indicated in Chronic dry cough or unproductive cough; Acute dry cough which is interfering with normal function or sleep.

Pharmacology

Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Dosage & Administration

Adults and Children over 12 years: 15 to 30 mg three to four times per day. However, 60 mg doses up to four times per day have been used without increased side effects.

Children between 6 and 12 years: 5-15 mg up to four times per day.

Children between 2 and 6 years: 2.5-5 mg up to four times per day.

Side Effects

Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after overdosage.

Overdose Effects

Symptoms: In mild overdose, tachycardia, hypertension, vomiting, mydriasis, diaphoresis, nystagmus, euphoria, loss of motor coordination, and giggling; in moderate intoxication, in addition to those listed above, hallucinations and a plodding ataxic gait; in severely intoxication, agitation or somnolence.

Management: treatment is symptomatic and supportive. Naloxone may be useful in reversing toxicity.

Storage Conditions

Store at 15-30° C

Acticol Syrup

  • Ambroxol Hydrochloride
  • 15 mg/5 ml
  • GlaxoSmithKline

Indications

This is indicated in-

  • Productive cough
  • Acute and chronic inflammatory disorders of upper and lower respiratory tracts associated with viscid mucus including acute and chronic bronchitis
  • Inflammatory disease of rhinopharyngeal tract (laryngitis, pharyngitis, sinusitis and rhinitis) associated with viscid mucus
  • Asthmatic bronchitis bronchial asthma with thick expectoration
  • Bronchiectasis
  • Chronic pneumonia etc.

Pharmacology

Ambroxol is the active metabolite of bromhexine and it has been proven that this metabolite possesses a greater bronchosecretolytic effect than bromhexine. It improves sputum rheology by hydrating mechanism leading to liquefaction of mucus in the lumen of respiratory tract, thus facilitating expectoration of mucus and reducing dyspnea. It stimulates production of phospholipids of surfactant by alveolar cells, thus contributing to the lowering of superficial tension in the alveoli. It also reduces bronchial hyperactivity. Ambroxol has anti inflammatory properties owing to the inhibitory effect on the production of cellular cytokines and arachidonic acid metabolites. In patients with COPD it traditionally improves airway patency.

Dosage & Administration

Average daily dose (preferably after meal):

Pediatric Drops:

  • 0-6 months: 0.5 ml 2 times a day
  • 6-12 months: 1 ml 2 times a day
  • 1-2 years: 1.25 ml 2 times a day

Syrup:

  • 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
  • 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
  • 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.

Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily.

Side Effects

Gastrointestinal side effects like epigastric pain, stomach overfill feeling may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema have been reported.

Storage Conditions

Protect from direct light exposure, Store in a dry place at a temperature not exceeding 30°C, Keep out of the reach of children.

Aerovil Syrup

  • Chlorpheniramine Maleate
  • 2 mg/5 ml
  • Beximco Pharmaceuticals Ltd.

Indications

Indicated mainly in allergic conditions including urticaria, sensitivity reactions, angioneurotic oedema, seasonal hay fever, vasomotor rhinitis, cough, common cold, motion sickness

Pharmacology

Chlorpheniramine is an alkylamine antihistamine. It is one of the most potent H1 blocking agents and is generally effective in relatively low doses. Chlorpheniramine is not so prone to produce drowsiness, readily absorbed from the gastro-intestinal tract, metabolised in the liver and excreted usually mainly as metabolised in the urine.

Dosage & Administration

Adults: 4 mg 3-4 times daily.

Children:

  • Up to 1( one) year: 1 mg twice daily
  • 1-5 years: 1 mg 3-4 times daily
  • 6-12 years: 2 mg 3-4 times daily or as directed by the physician

Side Effects

Drowsiness, dizziness, headache, psychomotor impairment, urinary retention, dry mouth, blurred vision and gastro intestinal disturbances, paradoxical stimulation may rarely occur, especially in high dosage or in children.

Alatrol Syrup

  • Cetirizine Hydrochloride
  • 5 mg/5 ml
  • Square Pharmaceuticals Ltd.

Indications

It is indicated for the relief of symptoms associated with seasonal & perennial allergic rhinitis. It is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma.

Pharmacology

Cetirizine Hydrochloride is a potent H1 receptor antagonist without any significant anticholinergic and antiserotonic effects. At pharmacologically active dose levels, it has almost no drowsiness effect and does not cause behavioural changes. It inhibits the histamine mediated early phase of the allergic reaction and also reduces the migration of inflammatory cells and the release of mediators associated with the late phase of the allergic reaction.

Dosage & Administration

Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily (or 1 teaspoonful twice daily).

Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily

Children 6 months to 2 years : 1/2 teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose as 1/2 teaspoonful every 12 hours.

Side Effects

The most common side effects that occurred more frequently on Cetirizine is somnolence.

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

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